Markus Degerman studied at Konstfack University of Arts, Crafts and Design in Stockholm from 1993-94 and at the Umeå Academy of Fine Arts from 1994-98. He has also studied at Nyckelviksskolan in Lidingö and the Royal Academy of Arts in Stockholm.
In 1999 Degerman founded the design and art studio Uglycute together with Andreas Nobel (interior architect), Jonas Nobel (artist) and Fredrik Stenberg (architect). Uglycute became a part of a generation of artists and designers that used their work to discuss taste, quality, class, gender and politics.
Due to the members different professions they came to work theoretically and practically as well as in pedagogy. Uglycute's first solo exhibition was held at the art gallery Marabouparken in Sundbyberg during 2012. In 2014 the studio designed their first chair, the stackable Stalker for Woodstockholm, that had a fluorescent paint that made it glow in the dark. Stalker was presented at the Stockholm Design Week the same year.
Together with Uglyute, Degerman has made interior architecture for companies, museums, and art galleries such as Cheap Monday and for the Swedish National Museum of Fine Arts and Magasin III in Stockholm.
From 2012 to 2019 Degerman held the position as professor in Fine Arts at the Academy of Arts at the UiT- the Arctic University of Tromsø, where he also was head of departments and programs. In 2019 Degerman started working as a dean at the Art and Craft department at the Oslo Academy of Arts, where he in 2021 was elected headmaster.